Cora Thiel and Svantje Tauber from the UZH Space Hub conduct pre­liminary tests on the production of human tissue from stem cells in zero gravity – a joint project with Airbus that is being brought to the pro­duction stage at Hangar 4 at the Switzerland Innovation Park Zurich (IPZ) in Dübendorf.
Cora Thiel and Svantje Tauber from the UZH Space Hub conduct pre­liminary tests on the production of human tissue from stem cells in zero gravity – a joint project with Airbus that is being brought to the pro­duction stage at Hangar 4 at the Switzerland Innovation Park Zurich (IPZ) in Dübendorf.

Research and Innovation

Promoting Diversity,
Reinforcing Strengths

UZH pro­motes diversity in research, making the most of its potential both strategical­ly and creative­ly by establi­shing inter­disciplinary specia­lizations.

UZH is com­mitted to embracing diverse and equi­table research cultures based on the values of in­dependence and free­dom, inter­disciplinarity, and close co­operation at the national and inter­national levels. At the same time, UZH’s research funding strategy is to further re­inforce its strengths in order to main­tain and expand its leading position in the inter­national re­search com­munity.

National Centers of Competence in Research

Together with the Uni­versity of Geneva and, since 2024, the Uni­versity of Neuchâtel, UZH is the home of the National Center of Competence in Research (NCCR) Evolving Language, which was launched in 2019. The NCCR, which entered its second fun­ding phase in 2024, investigates the emer­gence and develop­ment of language. It brings together research groups from the hu­manities and social sciences, as well as com­puter and natural sciences. The Swiss National Science Foundation (SNSF) is sup­porting this NCCR with CHF 20.4 million over the next four years. UZH is also in­volved in 10 other NCCRs.

University Research Priority Programs

The University Research Priority Programs (URPPs) have been a central instru­ment of priority and net­work funding at UZH since 2005. They are com­petitively tendered with a maximum term of 12 years and combine research expertise from various disciplines to solve scientific issues in socially re­levant areas.

The eight URPPs of the second series expired in 2024, with very pleasing results. Al­together, 36 new professor­ships with new de­nominations were created, third-party funds amount­ing to over CHF 270 million were raised and 473 early-career re­searchers were trained, some of whom were ap­pointed to inter­nationally re­nowned chairs.

Thanks to their re­search results, the URPPs have con­tributed to the re­form of financial market regulation, ex­panded the under­standing of bio­diversity, built bridges between cancer research and cancer treat­ments, shed light on the dynamics of social networks, advanced the develop­ment of artificial photo­synthesis for energy pro­duction, analyzed the adap­tation of patho­gens to changing environ­mental conditions, and set standards in spatial inter­disciplinary language re­search and the under­standing of healthy aging. The URPPs also achieved success in policy making. The WHO, for example, adopted the de­finition of healthy aging for­mulated by the URPP Dynamics of Healthy Aging.

UZH’s funding strategy aims to make a lasting impact, meaning that many of the skills, net­works, methodo­logies and techno­logies developed as part of the URPPs will benefit UZH and society in the long term. The URPPs in the second series gave rise to the Center for Financial Market Regulation, the Comprehensive Cancer Center Zurich, the Healthy Longevity Center, the national techno­logy plat­form Linguistic Research Infrastructure (LiRI) and the UZH Blockchain Center, among others.

UZH provides a total of around CHF 16 million per year to the URPPs. The second of three four-year funding phases for the five URPPs in the third series began in 2024. These URPPs focus on the biology of learning, digital religions, equality and in­equality, human re­production and rare diseases.

Promoting diversity strategically: TRANSFORM

The TRANSFORM fun­ding stream, launched at UZH in 2021, has become estab­lished as an im­portant long-term instru­ment for pro­moting re­search concen­trations and net­works. For example, the Vetsuisse Faculty, the Faculty of Medicine and the Faculty of Science jointly founded the first One Health Institute at a European uni­versity with the help of seed funding from TRANSFORM in 2022. The One Health ap­proach to research com­bines the expertise of different fields in order to investi­gate the inter­relations between human, animal and environ­mental health, with the aim of tackling global health prob­lems more ef­fectively. The first of three plan­ned professor­ships was filled in 2024.

The One Health Institute was found­ed with the strategic inten­tion of strength­ening inter­national co­operation between the in­volved disciplines. In 2022, UZH joined the Una Europa university alliance, which also pro­motes One Health as one of its focus areas. A positive con­sequence of this is that UZH is now part of the most im­portant European One Health network. This opens up many op­portunities for it to capitalize on cross-border synergies and leverage its potential inter­nationally. At the Una Europa General Assembly, which was held in Zurich in June 2024, the topic of One Health was the focus of mutual ex­change at the ini­tiative of UZH.

At a meeting organized along with Swissnex in Bangalore, India, in December 2024, de­legations from the Indian Institute of Science, Makerere University in Uganda and UZH deepened their relation­ships and paved the way for closer global col­laboration in the fields of One Health and Planetary Health. Switzerland and India have main­tained good relations in the fields of education, research and in­novation for many years, and this formed the basis for the meeting, which will be fol­lowed by concrete col­laborations (joint doctoral training and research projects) in various disciplines.

Three new TRANSFORM projects

In 2024, UZH ap­proved seed funding in the context of TRANSFORM for three projects aimed to bring about long-term structural changes to the re­search land­scape at UZH:

  • Establishment of an inter­disciplinary Department of Archaeology, Classical Philology and Classical Studies (IAKA) by merging three existing depart­ments.
  • Establishment of a Center for Engineered Immunotherapy (CEI) with the aim of accele­rating cutting-edge inter­disciplinary research at UZH and the clinical application of innovative immuno­therapies.
  • Establishment of a new Center for Research Synthesis for research, con­sulting and teaching on quality-assuring research methods (reproducibility, biostatistics, open research data, etc.) and the for­mation of net­works in this area.

Shaping the future: innovation

UZH creates essential foundations for an in­novative economy and society. Its aim is to further re­inforce the impact of these ef­forts. The UZH Innovation Hub has a central role to play here. It provides targeted support to individuals and networks in order to transfer re­search results and creative ideas to practical ap­plication.

In 2024, the success of the UZH Entrepreneur Fellowship Program was sup­plemented by the new Sustainable Society funding stream, which sup­ports re­searchers from all disciplines when it comes to implementing pro­mising ideas for sustainable develop­ment. At the same time, the program to support entrepreneurial skills for post­doctoral researchers was introduced in 2024. This means that suitable op­portunities are now available for all academic career stages at UZH.

The new DRIVE (Drive Research-Based Innovation Ecosystems) program was also launched in 2024. Building on UZH members’ own initiatives, it sup­ports the formation of high-power net­works with the aim of creating links between science, economy and society – thus ac­celerating the transfer of ideas and techno­logy.

The Healthy Longevity Center and the UZH Space Hub are two examples of success­ful network structures that were created thanks to seed funding from UZH. Both are now providing ef­fective impetus in the canton of Zurich and beyond. A promising environ­ment for col­laboration between research and industry in the aero­space sector is currently being created at the Switzerland Innovation Park Zurich (IPZ) in Dübendorf, for example. The UZH Space Hub, with its strong inter­disciplinary research and its wide inter­national net­work, is a driving factor in this endeavor. In 2024, it moved to a new location at Hangar 4, joining the IPZ on site. In addition, the UZH Space Hub entered into a strategic partner­ship with the newly founded Center for Space & Aviation, a hub that brings together research and the emerging new space economy. In December 2024, a joint memoran­dum of under­standing paved the way for the inter­national space con­sortium Starlab Space to set up at the IPZ, making it Starlab’s future European site. The com­pany plans to build its third-ever science park in Dübendorf. A large part of the logistics for the planned Starlab space station will also take place here.

Researching cultural heritage

UZH has joined the Cultural Heritage doctoral program of the Una Europa uni­versity alliance. This means it now parti­cipates in developing a varied trans­national re­search eco­system com­bining cultural studies, archaeology and historical studies. The pro­gram offers PhD candidates from UZH and the 10 partner uni­versities the op­portunity to con­duct research in a multi­lingual and inter­disciplinary environ­ment. The PhD candi­dates benefit from the broad expertise of renowned univer­sities and a cor­respondingly wide range of op­portunities for exchange and super­vision. Those who success­fully complete the program receive a doctorate from two univer­sities in the alliance.

Tissue samples are stored in liquid nitrogen tanks at the Institute of Pathology and Molecular Pathology. These samples can be thawed and reused later for research in precision medicine.

Promoting precision medicine

Bespoke medical therapies in­crease long-term ef­ficacy and reduce side ef­fects. This is why UZH specifical­ly pro­motes the develop­ment of precision medicine. Large amounts of data from re­search and clinical facilities are re­quired for more ac­curate diagnoses, more re­liable prognoses and treat­ments that are better adapted to individual patients’ needs. In ad­dition, advances in precision medicine require strong institutional net­works. The LOOP Zurich, the Tumor Profiler Center and the Comprehensive Cancer Center Zurich are bringing to­gether their ex­pertise under the umbrella of University Medicine Zurich (UMZH), which includes UZH, ETHZ and the uni­versity’s four hos­pitals. Since 2024, UMZH has also been working with the Bellinzona regional hos­pital and the cantonal hos­pital of Lucerne on the topic of precision medicine.

The Biomedical Informatics Platform (BMIP), the first beta version of which will be launched at the begin­ning of 2025, plays a key role. It fol­lows the same strict data pro­tection require­ments as hospitals when mana­ging patient and research data. In the future, the hospitals’ bio­banks will also be linked to the BMIP. Biobanks store bodily tis­sues and fluids, as well as as­sociated data. Access to bio­banks with molecular in­formation pro­mises a further boost in the develop­ment of precision medicine.

Linking clinical practice and research

A close con­nection between re­search, teaching and clinical care is cru­cial for the growth of Zurich as a medical hub. In 2024, the University Medicine Zurich (UMZH) net­work launched the Advanced Clinician Scientist Program as part of its um­brella stra­tegy. This pro­gram is de­signed for physicians who have already com­pleted specialist training, are actively in­volved in both clinical practice and research, and are pursuing an academic career. The funding pro­gram provides sup­port for dedicated re­search time, tech­nical staff and re­sources for an in­dependent project.

Bringing medical innovations to market

The Translational Medicine Accelerator (TMA) supports re­searchers bringing medical in­novations to market, and in doing so allows them to become entre­preneurs. The pro­gram analyzes ideas for medical dia­gnostics, products, thera­pies and digital health services. It then provides as­sistance for their further develop­ment, up to and including success­fully financing a spin-off. Over the past three years, more than 100 projects at various stages of develop­ment have been sup­ported. In 2024, the TMA ex­panded its offerings: it now also sup­ports re­searchers col­laborating with the private sector. The aim is for UZH medical re­searchers and industrial part­ners to mutually benefit from each other’s expertise, so they can col­laborate to forge new paths for the be­nefit of patients.

Shaping the Future Effectively

Developing sus­tainable solutions to social problems, working on com­prehensive and precise medicine for all, researching and sup­porting positive develop­ment in children and adole­scents, assessing the conse­quences of climate change and bio­diversity loss, and collecting objects with care and respect: UZH re­searchers are working together in an inter­disciplinary way to tackle current challenges and develop in­novative ideas for the future.

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